| Reaction Details |
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 | Report a problem with these data |
| Target | D-alanyl-D-alanine carboxypeptidase |
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| Ligand | BDBM50337094 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_718756 (CHEMBL1681054) |
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| IC50 | 270±n/a nM |
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| Citation |  Woon, EC; Zervosen, A; Sauvage, E; Simmons, KJ; Zivec, M; Inglis, SR; Fishwick, CW; Gobec, S; Charlier, P; Luxen, As Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors ACS Med Chem Lett2:219-223 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| D-alanyl-D-alanine carboxypeptidase |
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| Name: | D-alanyl-D-alanine carboxypeptidase |
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| Synonyms: | DAC_ACTSP | dac |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54928.46 |
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| Organism: | Actinomadura sp. (strain R39) |
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| Description: | ChEMBL_822544 |
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| Residue: | 538 |
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| Sequence: | MKQSSPEPLRPRRTGGRGGARRAAALVTIPLLPMTLLGASPALADASGARLTELREDIDA
ILEDPALEGAVSGVVVVDTATGEELYSRDGGEQLLPASNMKLFTAAAALEVLGADHSFGT
EVAAESAPGRRGEVQDLYLVGRGDPTLSAEDLDAMAAEVAASGVRTVRGDLYADDTWFDS
ERLVDDWWPEDEPYAYSAQISALTVAHGERFDTGVTEVSVTPAAEGEPADVDLGAAEGYA
ELDNRAVTGAAGSANTLVIDRPVGTNTIAVTGSLPADAAPVTALRTVDEPAALAGHLFEE
ALESNGVTVKGDVGLGGVPADWQDAEVLADHTSAELSEILVPFMKFSNNGHAEMLVKSIG
QETAGAGTWDAGLVGVEEALSGLGVDTAGLVLNDGSGLSRGNLVTADTVVDLLGQAGSAP
WAQTWSASLPVAGESDPFVGGTLANRMRGTAAEGVVEAKTGTMSGVSALSGYVPGPEGEL
AFSIVNNGHSGPAPLAVQDAIAVRLAEYAGHQAPEGARMMRGPVQGSGELECSWVQAC
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| BDBM50337094 |
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| n/a |
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| Name | BDBM50337094 |
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| Synonyms: | (S)-1-(2-Fluoro-6-phenylbenzamido)ethaneboronic acid | CHEMBL1672822 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H15BFNO3 |
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| Mol. Mass. | 287.094 |
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| SMILES | C[C@@H](NC(=O)c1c(F)cccc1-c1ccccc1)B(O)O |r| |
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| Structure | 
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