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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Matrix protein 2 [1-96] | ||
| Ligand | BDBM50343549 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_747076 (CHEMBL1777442) | ||
| IC50 | 33500±n/a nM | ||
| Citation |  Duque, MD; Ma, C; Torres, E; Wang, J; Naesens, L; Juárez-Jiménez, J; Camps, P; Luque, FJ; DeGrado, WF; Lamb, RA; Pinto, LH; Vázquez, S Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus. J Med Chem54:2646-57 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Matrix protein 2 [1-96] | |||
| Name: | Matrix protein 2 [1-96] | ||
| Synonyms: | M | M2_I72A2 | Matrix protein 2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 11051.96 | ||
| Organism: | Influenza A virus | ||
| Description: | ChEMBL_1453980 | ||
| Residue: | 96 | ||
| Sequence: |
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| BDBM50343549 | |||
| n/a | |||
| Name | BDBM50343549 | ||
| Synonyms: | 3-Azahexacyclo[7.6.0.0(1,5).0(5,12).0(6,10).0(11,15)]pentadeca-7,13-diene Hydrochloride | CHEMBL1774319 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H15N | ||
| Mol. Mass. | 197.2756 | ||
| SMILES | C1NCC23C4C=CC5C4C4C(C=CC24)C135 |c:5,12,TLB:4:3:11.12:9,7:14:11.12:9,6:7:4:13.9,0:14:4:13.9,0:14:8:5.6,2:3:8:5.6,THB:8:9:14.3:11.12,12:13:4:14.7,12:13:4.8:14.10,13:3:8:5.6,10:14:4:13.9,10:9:4:14.7,10:14:8:5.6,9:8:14.3:5.6,0:14:11.12:9,2:3:11.12:9,(27.24,-25.38,;29.04,-26.14,;27.89,-24.75,;27.89,-22.62,;29.02,-21.83,;30.43,-22.65,;29.91,-23.76,;28.62,-23.1,;28.74,-20.39,;26.08,-20.42,;25.96,-23.13,;24.58,-23.82,;25.23,-22.66,;26.36,-21.86,;27.24,-23.79,)| | ||
| Structure | 
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