| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone-lysine N-methyltransferase SETD7 |
|---|
| Ligand | BDBM50353131 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_768576 (CHEMBL1832595) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Liu, F; Barsyte-Lovejoy, D; Allali-Hassani, A; He, Y; Herold, JM; Chen, X; Yates, CM; Frye, SV; Brown, PJ; Huang, J; Vedadi, M; Arrowsmith, CH; Jin, J Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem54:6139-50 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone-lysine N-methyltransferase SETD7 |
|---|
| Name: | Histone-lysine N-methyltransferase SETD7 |
|---|
| Synonyms: | Histone-lysine N-methyltransferase SETD7 | KIAA1717 | KMT7 | SET domain-containing protein 7/9 (Set7/9) | SET7 | SET9 | SETD7 | SETD7_HUMAN |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40691.12 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8WTS6 |
|---|
| Residue: | 366 |
|---|
| Sequence: | MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE
GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW
IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP
HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT
VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT
PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF
QATQQK
|
|
|
|---|
| BDBM50353131 |
|---|
| n/a |
|---|
| Name | BDBM50353131 |
|---|
| Synonyms: | CHEMBL1829304 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H59N7O2 |
|---|
| Mol. Mass. | 621.8994 |
|---|
| SMILES | COc1cc2c(NC3CCN(CC3)C3CCCCC3)nc(nc2cc1OCCCN1CCCCC1)N1CCCN(CC1)C(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
