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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50354063 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_770872 (CHEMBL1837820) | ||
| Ki | 16.1±n/a nM | ||
| Citation |  Packiarajan, M; Marzabadi, MR; Desai, M; Lu, Y; Noble, SA; Wong, WC; Jubian, V; Chandrasena, G; Wolinsky, TD; Zhong, H; Walker, MW; Wiborg, O; Andersen, K Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. Bioorg Med Chem Lett21:5436-41 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50354063 | |||
| n/a | |||
| Name | BDBM50354063 | ||
| Synonyms: | CHEMBL1836332 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H25N3O3S2 | ||
| Mol. Mass. | 407.55 | ||
| SMILES | CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCOc3ccccc-23)s1 |r,wU:6.5,wD:9.12,(55.11,-10.15,;53.77,-10.92,;53,-12.26,;54.54,-12.26,;52.43,-10.14,;51.09,-10.91,;49.75,-10.14,;48.42,-10.91,;47.08,-10.13,;47.07,-8.59,;48.42,-7.82,;49.76,-8.6,;45.74,-7.8,;44.39,-8.55,;43.03,-7.93,;42.02,-9.03,;42.76,-10.34,;42.14,-11.82,;40.63,-12.21,;39.41,-11.27,;39.38,-9.67,;37.99,-9.15,;37.74,-7.69,;38.89,-6.73,;40.29,-7.25,;40.53,-8.72,;44.23,-10.04,)| | ||
| Structure | 
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