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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50354065 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_770872 (CHEMBL1837820) | ||
| Ki | 27±n/a nM | ||
| Citation |  Packiarajan, M; Marzabadi, MR; Desai, M; Lu, Y; Noble, SA; Wong, WC; Jubian, V; Chandrasena, G; Wolinsky, TD; Zhong, H; Walker, MW; Wiborg, O; Andersen, K Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. Bioorg Med Chem Lett21:5436-41 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50354065 | |||
| n/a | |||
| Name | BDBM50354065 | ||
| Synonyms: | CHEMBL1836325 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H24FN3O2S2 | ||
| Mol. Mass. | 409.541 | ||
| SMILES | CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCCc3ccc(F)cc-23)s1 |r,wU:5.4,wD:8.11,(26.46,-46.27,;25.36,-45.19,;26.16,-43.86,;24.61,-43.83,;24.14,-46.14,;22.8,-45.35,;21.45,-46.11,;20.12,-45.32,;20.14,-43.78,;21.48,-43.01,;22.81,-43.8,;18.81,-42.99,;17.47,-43.75,;16.1,-43.13,;15.08,-44.24,;15.82,-45.55,;15.2,-47.03,;13.69,-47.42,;12.48,-46.48,;12.44,-44.87,;11.05,-44.36,;10.8,-42.89,;11.95,-41.93,;11.69,-40.41,;13.35,-42.46,;13.59,-43.93,;17.3,-45.25,)| | ||
| Structure | 
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