| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-5 [D153N] |
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| Ligand | BDBM50355087 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_772790 (CHEMBL1837529) |
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| IC50 | 367400±n/a nM |
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| Citation |  Teixeira, TS; Freitas, RF; Abrahão, O; Devienne, KF; de Souza, LR; Blaber, SI; Blaber, M; Kondo, MY; Juliano, MA; Juliano, L; Puzer, L Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7. Bioorg Med Chem Lett21:6112-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-5 [D153N] |
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| Name: | Kallikrein-5 [D153N] |
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| Synonyms: | KLK-L2 | KLK5 | KLK5_HUMAN | Kallikrein 5 | Kallikrein-5 | Kallikrein-like protein 2 | SCTE | Stratum corneum tryptic enzyme |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32031.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1282456 |
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| Residue: | 293 |
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| Sequence: | MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
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| BDBM50355087 |
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| n/a |
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| Name | BDBM50355087 |
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| Synonyms: | CHEMBL1833982 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14O6 |
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| Mol. Mass. | 302.2788 |
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| SMILES | COc1cc(O)c2c(O)c3c(cc(C)oc3=O)c(OC)c2c1 |
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| Structure | 
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