Reaction Details | |||
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Target | Kallikrein-7 | ||
Ligand | BDBM50355088 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_772792 (CHEMBL1837531) | ||
IC50 | 135300±n/a nM | ||
Citation | Teixeira, TS; Freitas, RF; Abrahão, O; Devienne, KF; de Souza, LR; Blaber, SI; Blaber, M; Kondo, MY; Juliano, MA; Juliano, L; Puzer, L Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7. Bioorg Med Chem Lett21:6112-5 (2011) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Kallikrein-7 | |||
Name: | Kallikrein-7 | ||
Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein | ||
Type: | PROTEIN | ||
Mol. Mass.: | 27535.05 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_1469257 | ||
Residue: | 253 | ||
Sequence: |
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BDBM50355088 | |||
n/a | |||
Name | BDBM50355088 | ||
Synonyms: | CHEMBL1834754 | ||
Type | Small organic molecule | ||
Emp. Form. | C30H26O10 | ||
Mol. Mass. | 546.5214 | ||
SMILES | COc1cc2cc3C[C@@H](C)OC(=O)c3c(O)c2c(O)c1-c1c(OC)cc2cc3C[C@@H](C)OC(=O)c3c(O)c2c1O |r,wU:8.8,29.32,(38.37,-41.46,;38.37,-39.92,;37.04,-39.15,;35.7,-39.92,;34.37,-39.14,;33.04,-39.92,;31.71,-39.15,;30.37,-39.93,;29.04,-39.15,;27.7,-39.92,;29.04,-37.6,;30.38,-36.84,;30.38,-35.3,;31.71,-37.61,;33.04,-36.83,;33.04,-35.29,;34.37,-37.6,;35.7,-36.84,;35.7,-35.3,;37.03,-37.6,;38.36,-36.83,;38.36,-35.28,;37.03,-34.51,;37.03,-32.97,;39.7,-34.51,;41.03,-35.28,;42.35,-34.51,;43.69,-35.27,;45.02,-34.5,;46.36,-35.28,;47.7,-34.51,;46.36,-36.82,;45.02,-37.59,;45.01,-39.13,;43.69,-36.82,;42.36,-37.6,;42.36,-39.14,;41.02,-36.82,;39.7,-37.59,;39.7,-39.13,)| | ||
Structure |