| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase-like 2 |
|---|
| Ligand | BDBM25919 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774408 (CHEMBL1908625) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase-like 2 |
|---|
| Name: | Cyclin-dependent kinase-like 2 |
|---|
| Synonyms: | 2.7.11.22 | CDKL2 | CDKL2_HUMAN | Protein kinase p56 KKIAMRE | Serine/threonine-protein kinase KKIAMRE |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 56031.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92772 |
|---|
| Residue: | 493 |
|---|
| Sequence: | MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
DSGADLPQMEHQH
|
|
|
|---|
| BDBM25919 |
|---|
| n/a |
|---|
| Name | BDBM25919 |
|---|
| Synonyms: | BMS-345541 | BMS345541 | CHEMBL471496 | N-(2-aminoethyl)-3,12-dimethyl-2,5,8-triazatricyclo[7.4.0.0^{2,6}]trideca-1(13),3,5,7,9,11-hexaen-7-amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H17N5 |
|---|
| Mol. Mass. | 255.3183 |
|---|
| SMILES | Cc1cnc2c(NCCN)nc3ccc(C)cc3n12 |
|---|
| Structure | 
|
|---|
Search and Browse
