| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ephrin type-B receptor 1 |
|---|
| Ligand | BDBM36409 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774434 (CHEMBL1908651) |
|---|
| Kd | 1900±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ephrin type-B receptor 1 |
|---|
| Name: | Ephrin type-B receptor 1 |
|---|
| Synonyms: | ELK | EPH receptor B1 | EPHB1 | EPHB1_HUMAN | EPHT2 | Ephrin receptor | Ephrin type-B receptor 1 | HEK6 | NET |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 109882.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EPH receptor B1 EPHB1 HUMAN::P54762 |
|---|
| Residue: | 984 |
|---|
| Sequence: | MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQV
CNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSV
IATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDY
GACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYC
NGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPI
CTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIIC
KKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPP
QHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFN
SSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLP
LIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTY
EDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEK
QRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQ
LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTS
SLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD
YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ
PLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAG
HQKKILNSIHSMRVQISQSPTAMA
|
|
|
|---|
| BDBM36409 |
|---|
| n/a |
|---|
| Name | BDBM36409 |
|---|
| Synonyms: | 2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol, PP242 | CID24905147 | US10172858, Table 2.1 | US9828378, # 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H16N6O |
|---|
| Mol. Mass. | 308.3378 |
|---|
| SMILES | CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
