| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Wee1-like protein kinase 2 |
|---|
| Ligand | BDBM50355500 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774226 (CHEMBL1908443) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Wee1-like protein kinase 2 |
|---|
| Name: | Wee1-like protein kinase 2 |
|---|
| Synonyms: | WEE1B | WEE2 | WEE2_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 62923.50 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_774226 |
|---|
| Residue: | 567 |
|---|
| Sequence: | MDDKDIDKELRQKLNFSYCEETEIEGQKKVEESREASSQTPEKGEVQDSEAKGTPPWTPL
SNVHELDTSSEKDKESPDQILRTPVSHPLKCPETPAQPDSRSKLLPSDSPSTPKTMLSRL
VISPTGKLPSRGPKHLKLTPAPLKDEMTSLALVNINPFTPESYKKLFLQSGGKRKIRGDL
EEAGPEEGKGGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVYKCIKRLDGCVYAI
KRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMIIQNEYCNGGSLQAA
ISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFICHKMQSESSGVIE
EVENEADWFLSANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQEDYRHLPKADIFAL
GLTIAVAAGAESLPTNGAAWHHIRKGNFPDVPQELSESFSSLLKNMIQPDAEQRPSAAAL
ARNTVLRPSLGKTEELQQQLNLEKFKTATLERELREAQQAQSPQGYTHHGDTGVSGTHTG
SRSTKRLVGGKSARSSSFTSGEREPLH
|
|
|
|---|
| BDBM50355500 |
|---|
| n/a |
|---|
| Name | BDBM50355500 |
|---|
| Synonyms: | CHEMBL1908394 | US9695172, GSK461364 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H28F3N5O2S |
|---|
| Mol. Mass. | 543.604 |
|---|
| SMILES | C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(CN3CCN(C)CC3)cc12)c1ccccc1C(F)(F)F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
