| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase kinase 1 |
|---|
| Ligand | BDBM26300 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774623 (CHEMBL1908840) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calcium/calmodulin-dependent protein kinase kinase 1 |
|---|
| Name: | Calcium/calmodulin-dependent protein kinase kinase 1 |
|---|
| Synonyms: | CAMKK1 | CAMKKA | CaM-kinase kinase alpha | KKCC1_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 55727.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_774623 |
|---|
| Residue: | 505 |
|---|
| Sequence: | MEGGPAVCCQDPRAELVERVAAIDVTHLEEADGGPEPTRNGVDPPPRARAASVIPGSTSR
LLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRRPTIESHHVAISDAE
DCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQ
AAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVME
VPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF
EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILA
LHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSE
EEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMSAPGNL
LVKEGFGEGGKSPELPGVQEDEAAS
|
|
|
|---|
| BDBM26300 |
|---|
| n/a |
|---|
| Name | BDBM26300 |
|---|
| Synonyms: | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide | CHEMBL215152 | cid_16007391 | pyrazoloquinazoline deriv., 34 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H30FN7O3 |
|---|
| Mol. Mass. | 507.5599 |
|---|
| SMILES | CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
