| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 14 |
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| Ligand | BDBM50355496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_774550 (CHEMBL1908767) |
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| Kd | 870±n/a nM |
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| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 14 |
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| Name: | Cyclin-dependent kinase 14 |
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| Synonyms: | CDK14 | CDK14_HUMAN | KIAA0834 | PFTK1 | Serine/threonine-protein kinase PFTAIRE-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53075.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774550 |
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| Residue: | 469 |
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| Sequence: | MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSS
PSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIR
EASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQL
LRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPP
DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV
HSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFS
DLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
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| BDBM50355496 |
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| n/a |
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| Name | BDBM50355496 |
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| Synonyms: | CHEMBL1908397 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O |
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| Mol. Mass. | 332.399 |
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| SMILES | O=C(N1CCNCC1)c1ccc(\C=C\c2n[nH]c3ccccc23)cc1 |
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| Structure | 
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