| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform alpha-like |
|---|
| Ligand | BDBM4851 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774203 (CHEMBL1908420) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase I isoform alpha-like |
|---|
| Name: | Casein kinase I isoform alpha-like |
|---|
| Synonyms: | CSNK1A1L | Casein kinase I isoform alpha-like | KC1AL_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39105.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_586447 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYE
SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKK
MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
|
|
|
|---|
| BDBM4851 |
|---|
| n/a |
|---|
| Name | BDBM4851 |
|---|
| Synonyms: | (4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine | (A) PTK787 | CGP 79787 | CHEMBL101253 | CHEMBL75232 | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-1-phthalazinamine | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine | PTK-787 | PTK787 | ZK222584 | cid_151194 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H15ClN4 |
|---|
| Mol. Mass. | 346.813 |
|---|
| SMILES | Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
