| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
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| Ligand | BDBM50355500 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_774231 (CHEMBL1908448) |
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| Kd | 6700±n/a nM |
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| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
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| Name: | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
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| Synonyms: | KIAA0589 | PI51C_HUMAN | PIP5K1-gamma | PIP5K1C | PIP5KIgamma | Phosphatidylinositol 4-phosphate 5-kinase type I gamma | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma | PtdIns(4)P-5-kinase 1 gamma |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73241.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508846 |
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| Residue: | 668 |
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| Sequence: | MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGH
RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGS
NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVT
SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN
ILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK
TLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMES
IQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG
DTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQI
PSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP
SETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEAS
PAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPP
ASDGESDT
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| BDBM50355500 |
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| n/a |
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| Name | BDBM50355500 |
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| Synonyms: | CHEMBL1908394 | US9695172, GSK461364 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28F3N5O2S |
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| Mol. Mass. | 543.604 |
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| SMILES | C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(CN3CCN(C)CC3)cc12)c1ccccc1C(F)(F)F |r| |
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| Structure | 
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