| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50357803 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_787443 (CHEMBL1919362) |
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| IC50 | 150±n/a nM |
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| Citation |  Malamas, MS; Ni, Y; Erdei, J; Stange, H; Schindler, R; Lankau, HJ; Grunwald, C; Fan, KY; Parris, K; Langen, B; Egerland, U; Hage, T; Marquis, KL; Grauer, S; Brennan, J; Navarra, R; Graf, R; Harrison, BL; Robichaud, A; Kronbach, T; Pangalos, MN; Hoefgen, N; Brandon, NJ Highly potent, selective, and orally active phosphodiesterase 10A inhibitors. J Med Chem54:7621-38 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50357803 |
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| n/a |
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| Name | BDBM50357803 |
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| Synonyms: | CHEMBL1916113 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17FN4O |
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| Mol. Mass. | 336.3629 |
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| SMILES | COc1cc(F)cc2c1nc(C)c1c(C)nc(-c3ccncc3C)n21 |
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| Structure | 
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