| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
|---|
| Ligand | BDBM50357980 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_786345 (CHEMBL1920541) |
|---|
| Ki | 228±n/a nM |
|---|
| Citation |  Zajdel, P; Marciniec, K; Maslankiewicz, A; Paluchowska, MH; Satala, G; Partyka, A; Jastrzebska-Wiesek, M; Wróbel, D; Wesolowska, A; Duszynska, B; Bojarski, AJ; Pawlowski, M Arene- and quinoline-sulfonamides as novel 5-HT7 receptor ligands. Bioorg Med Chem19:6750-9 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 7 |
|---|
| Name: | 5-hydroxytryptamine receptor 7 |
|---|
| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 53573.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34969 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
|
|
|
|---|
| BDBM50357980 |
|---|
| n/a |
|---|
| Name | BDBM50357980 |
|---|
| Synonyms: | CHEMBL1917346 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H25N3O2S |
|---|
| Mol. Mass. | 395.518 |
|---|
| SMILES | O=S(=O)(NCCCCN1CCc2ccccc2C1)c1cnc2ccccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
