| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
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| Ligand | BDBM50360740 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_796444 (CHEMBL1937759) |
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| EC50 | 190±n/a nM |
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| Citation |  Nomura, M; Yumoto, K; Shinozaki, T; Isogai, S; Takano, Y; Murakami, K Discovery of cyclic amine-substituted benzoic acids as PPARa agonists. Bioorg Med Chem Lett22:334-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor alpha |
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| Name: | Peroxisome proliferator-activated receptor alpha |
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| Synonyms: | NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR-alpha | PPARA | PPARA_CANLF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52119.89 |
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| Organism: | Canis familiaris |
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| Description: | ChEMBL_796444 |
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| Residue: | 468 |
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| Sequence: | MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFSFTEYQYLGSG
PGSDGSVITDTLSPAPSPSSVTHPAAPGGAEEPSSVALNIECRICGDRASGYHYGVHACE
GCKGFFRRTIRLKLAYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEQDPEDAETADLKSLAKRIYEAYLKNFNMNKVKARVILAGKASNNPPFV
IHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKSIPGFANL
DLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLKLHLQTNHPDNI
FLFPKLLQKMADLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY
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| BDBM50360740 |
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| n/a |
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| Name | BDBM50360740 |
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| Synonyms: | CHEMBL1934476 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22ClN3O3S |
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| Mol. Mass. | 455.957 |
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| SMILES | Cc1nc(sc1C(=O)N[C@H]1CCCN(C1)c1cccc(c1)C(O)=O)-c1ccc(Cl)cc1 |r| |
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| Structure | 
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