| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptides B/W receptor type 1 |
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| Ligand | BDBM50362410 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_797952 (CHEMBL1942829) |
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| IC50 | 18±n/a nM |
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| Citation |  Anthony Romero, F; Hastings, NB; Moningka, R; Guo, Z; Wang, M; Di Salvo, J; Lei, Y; Trusca, D; Deng, Q; Tong, V; Terebetski, JL; Ball, RG; Ujjainwalla, F The discovery of potent antagonists of NPBWR1 (GPR7). Bioorg Med Chem Lett22:1014-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptides B/W receptor type 1 |
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| Name: | Neuropeptides B/W receptor type 1 |
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| Synonyms: | GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36111.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_119607128 |
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| Residue: | 328 |
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| Sequence: | MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA
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| BDBM50362410 |
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| n/a |
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| Name | BDBM50362410 |
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| Synonyms: | CHEMBL1940542 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H34BrN5O2S2 |
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| Mol. Mass. | 616.636 |
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| SMILES | COc1ccc(cc1)C1(CCC1)N[C@@H]1CC[C@@H]([C@H](C1)c1ccsc1)C(=O)N1CCN(CC1)c1nnc(Br)s1 |r| |
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| Structure | 
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