| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50280515 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_226539 |
|---|
| Ki | 10000±n/a nM |
|---|
| Citation |  Rajagopalan, P; Scribner, R; Pennev, P; Schmidt, W; Tam, S; Steinfels, G; Cook, L DuP 747: a new, potent, kappa opioid analgesic. Synthesis and pharmacology1. Bioorg Med Chem Lett2:715-720 (1992) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25124.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99720 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM50280515 |
|---|
| n/a |
|---|
| Name | BDBM50280515 |
|---|
| Synonyms: | 2-(3,4-Dichloro-phenyl)-N-methyl-N-((1S,2S)-2-pyrrolidin-1-yl-1,2,3,4-tetrahydro-naphthalen-1-yl)-acetamide; hydrochloride | CHEMBL538806 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H26Cl2N2O |
|---|
| Mol. Mass. | 417.371 |
|---|
| SMILES | CN([C@@H]1[C@H](CCc2ccccc12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
