| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50280516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_226539 |
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| Ki | 5160±n/a nM |
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| Citation |  Rajagopalan, P; Scribner, R; Pennev, P; Schmidt, W; Tam, S; Steinfels, G; Cook, L DuP 747: a new, potent, kappa opioid analgesic. Synthesis and pharmacology1. Bioorg Med Chem Lett2:715-720 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50280516 |
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| n/a |
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| Name | BDBM50280516 |
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| Synonyms: | 2-(3,4-Dichloro-phenyl)-N-((1S,2S)-5-methoxy-2-pyrrolidin-1-yl-1,2,3,4-tetrahydro-naphthalen-1-yl)-N-methyl-acetamide; compound with methanesulfonic acid | CHEMBL350943 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28Cl2N2O2 |
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| Mol. Mass. | 447.397 |
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| SMILES | COc1cccc2[C@@H]([C@H](CCc12)N1CCCC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 |
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| Structure | 
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