| Reaction Details |
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 | Report a problem with these data |
| Target | Diphosphomevalonate decarboxylase |
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| Ligand | BDBM50287715 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105296 |
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| IC50 | 15±n/a nM |
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| Citation |  Vlattas, I; Dellureficio, J; Ku, E; Bohacek, R; Xiaolu, Zhang Inhibition of mevalonate 5-pyrophosphate decarboxylase by a proline-containing transition state analog Bioorg Med Chem Lett6:2091-2096 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Diphosphomevalonate decarboxylase |
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| Name: | Diphosphomevalonate decarboxylase |
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| Synonyms: | MPD | MVD | MVD1_HUMAN | Mevalonate pyrophosphate decarboxylase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43408.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_105297 |
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| Residue: | 400 |
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| Sequence: | MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
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| BDBM50287715 |
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| n/a |
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| Name | BDBM50287715 |
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| Synonyms: | (2R)-1-({[(phosphonatooxy)phosphinato]oxy}acetyl)pyrrolidine-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C7H9NO10P2 |
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| Mol. Mass. | 329.0968 |
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| SMILES | [O-]C(=O)[C@H]1CCCN1C(=O)COP([O-])(=O)OP([O-])([O-])=O |
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| Structure | 
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