| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholinesterase |
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| Ligand | BDBM50289101 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29085 |
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| IC50 | >100000±n/a nM |
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| Citation |  Jaen, JC; Gregor, VE; Lee, C; Davis, R; Emmerling, M Acetylcholinesterase inhibition by fused dihydroquinazoline compounds Bioorg Med Chem Lett6:737-742 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholinesterase |
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| Name: | Acetylcholinesterase |
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| Synonyms: | ACES_RAT | Acetylcholinesterase (AChE) | Acetylcholinesterase and butyrylcholinesterase (AChE and BChE) | Acetylcholinesterase precursor | Acetylcholinesterase, AChE | Ache |
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| Type: | Enzyme |
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| Mol. Mass.: | 68193.62 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P37136 |
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| Residue: | 614 |
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| Sequence: | MRPPWYPLHTPSLASPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPV
SAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLIWIYGGGFYSGASSLDVYDGRFLAQVEGTVLVSM
NYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASV
GMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTEL
ISCLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPDALINTGDFQDLQVLVG
VVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPE
DPAHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGY
EIEFIFGLPLDPSLNYTVEERIFAQRLMQYWTNFARTGDPNDPRDSKSPRWPPYTTAAQQ
YVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQERCSDL
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| BDBM50289101 |
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| n/a |
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| Name | BDBM50289101 |
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| Synonyms: | 3-Chloro-12-thioxo-6,7,8,9,10,12-hexahydro-azepino[2,1-b]quinazolin-5-ium | 3-Chloro-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazoline-12-thione | CHEMBL350496 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13ClN2S |
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| Mol. Mass. | 264.774 |
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| SMILES | Clc1ccc2c(c1)nc1CCCCCn1c2=S |
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| Structure | 
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