| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid scaffolding protein |
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| Ligand | BDBM50082153 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_158969 |
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| IC50 | 45±n/a nM |
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| Citation |  Smith, DG; Gribble, AD; Haigh, D; Ife, RJ; Lavery, P; Skett, P; Slingsby, BP; Stacey, R; Ward, RW; West, A The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives. Bioorg Med Chem Lett9:3137-42 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Capsid scaffolding protein |
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| Name: | Capsid scaffolding protein |
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| Synonyms: | APNG | Assemblin | Assembly protein | Capsid protein P40 | Human cytomegalovirus protease (HCMV Pr) | Human herpes virus 5 capsid protein P40 | Protease precursor | SCAF_HCMVA | UL80 | pPR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73854.16 |
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| Organism: | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
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| Description: | ChEMBL_158958 |
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| Residue: | 708 |
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| Sequence: | MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLN
INHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWV
TQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRY
DKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVE
PPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASP
AVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGA
PVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDE
PPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARK
RLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASS
SPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGP
STAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
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| BDBM50082153 |
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| n/a |
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| Name | BDBM50082153 |
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| Synonyms: | 3-Hydroxyamino-N-[3-(5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-ylmethyl)-phenyl]-benzamide | CHEMBL322676 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17N3O4S |
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| Mol. Mass. | 407.442 |
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| SMILES | Cc1csc2nc(Cc3cccc(NC(=O)c4cccc(NO)c4)c3)oc(=O)c12 |
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| Structure | 
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