Ki Summary

Reaction Details

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Target

M-phase inducer phosphatase 2

Ligand

BDBM50093977

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_49032

IC50

27000±n/a nM

Citation

Takahashi, M; Dodo, K; Sugimoto, Y; Aoyagi, Y; Yamada, Y; Hashimoto, Y; Shirai, R Synthesis of the novel analogues of dysidiolide and their structure-activity relationship. Bioorg Med Chem Lett10:2571-4 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

M-phase inducer phosphatase 2

Name:

M-phase inducer phosphatase 2

Synonyms:

Type:

Protein

Mol. Mass.:

64985.27

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

580

Sequence:

MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ

BDBM50093977

n/a

Name

BDBM50093977

Synonyms:

4-{(S)-2-[(1S,2R,5S,8aS)-2,5-Dimethyl-5-(4-methyl-pent-4-enyl)-1,2,3,5,6,7,8,8a-octahydro-naphthalen-1-yl]-1-hydroxy-ethyl}-5-hydroxy-5H-furan-2-one | CHEMBL313595

Type

Small organic molecule

Emp. Form.

C24H36O4

Mol. Mass.

388.5402

SMILES

C[C@@H]1CC=C2[C@@H](CCC[C@@]2(C)CCCC(C)=C)[C@H]1C[C@H](O)C1=CC(=O)OC1O |c:3,t:23|

Structure