Reaction Details | |||
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Target | Nociceptin receptor | ||
Ligand | BDBM50087691 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_146124 | ||
Ki | 0.079000±n/a nM | ||
Citation | Röver, S; Wichmann, J; Jenck, F; Adam, G; Cesura, AM ORL1 receptor ligands: structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones. Bioorg Med Chem Lett10:831-4 (2000) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Nociceptin receptor | |||
Name: | Nociceptin receptor | ||
Synonyms: | Nociceptin/Orphanin FQ, NOP receptor | Nociceptin/mu opioid receptor | OPRX_RAT | Oor | Oprl | Oprl1 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 40531.08 | ||
Organism: | RAT | ||
Description: | Nociceptin/Orphanin FQ, NOP receptor 0 RAT::P35370 | ||
Residue: | 367 | ||
Sequence: |
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BDBM50087691 | |||
n/a | |||
Name | BDBM50087691 | ||
Synonyms: | 8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL166387 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H33N3O | ||
Mol. Mass. | 355.5169 | ||
SMILES | CC(C)[C@H]1CC[C@H](CC1)N1CCC2(CC1)N(CNC2=O)c1ccccc1 |wU:6.9,3.2,(2.69,-2.68,;3.46,-4.01,;2.69,-5.35,;5,-4.02,;5.77,-2.69,;7.31,-2.69,;8.06,-4.02,;7.31,-5.35,;5.77,-5.35,;9.6,-4.02,;10.37,-2.68,;11.91,-2.67,;12.68,-4.01,;11.91,-5.34,;10.37,-5.34,;13.56,-5.26,;15.03,-4.79,;15.03,-3.25,;13.59,-2.76,;13.1,-1.31,;13.1,-6.7,;11.58,-7.03,;11.11,-8.49,;12.14,-9.64,;13.66,-9.32,;14.12,-7.85,)| | ||
Structure |