| Reaction Details |
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 | Report a problem with these data |
| Target | Nociceptin receptor |
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| Ligand | BDBM50087686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_146124 |
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| Ki | 4.7±n/a nM |
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| Citation |  Röver, S; Wichmann, J; Jenck, F; Adam, G; Cesura, AM ORL1 receptor ligands: structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones. Bioorg Med Chem Lett10:831-4 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Nociceptin receptor |
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| Name: | Nociceptin receptor |
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| Synonyms: | Nociceptin/Orphanin FQ, NOP receptor | Nociceptin/mu opioid receptor | OPRX_RAT | Oor | Oprl | Oprl1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40531.08 |
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| Organism: | RAT |
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| Description: | Nociceptin/Orphanin FQ, NOP receptor 0 RAT::P35370 |
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| Residue: | 367 |
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| Sequence: | MESLFPAPYWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCI
GGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALC
KTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGV
PVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLR
GVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRF
CTALGYVNSCLNPILYAFLDENFKACFRKFCCASSLHREMQVSDRVRSIAKDVGLGCKTS
ETVPRPA
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|
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| BDBM50087686 |
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| n/a |
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| Name | BDBM50087686 |
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| Synonyms: | 8-Cycloheptyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL165885 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H29N3O |
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| Mol. Mass. | 327.4638 |
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| SMILES | O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCCC1 |
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| Structure | 
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