| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
|---|
| Ligand | BDBM50110681 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_161772 (CHEMBL767488) |
|---|
| IC50 | 2±n/a nM |
|---|
| Citation |  McCluskey, A; Keane, MA; Walkom, CC; Bowyer, MC; Sim, AT; Young, DJ; Sakoff, JA The first two cantharidin analogues displaying PP1 selectivity. Bioorg Med Chem Lett12:391-3 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
|---|
| Name: | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
|---|
| Synonyms: | Serine-threonine protein phosphatase 2A regulatory subunit |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49694.81 |
|---|
| Organism: | Gallus gallus |
|---|
| Description: | ChEMBL_161937 |
|---|
| Residue: | 426 |
|---|
| Sequence: | DDDVAEADIISTVEFNHCGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHE
PEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDG
RYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRIN
LWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASAL
CDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVE
TYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEA
SRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHHAWHPKENIIAVATTNNLYI
FQDKMN
|
|
|
|---|
| BDBM50110681 |
|---|
| n/a |
|---|
| Name | BDBM50110681 |
|---|
| Synonyms: | CHEMBL430266 | Calyculin-A |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C50H81N4O15P |
|---|
| Mol. Mass. | 1009.1697 |
|---|
| SMILES | COC[C@@H]([C@H](O)[C@H](O)C(=O)NCC[C@H](C)c1nc(\C=C\C[C@@H]2O[C@]3(C[C@@H](O)[C@@H]2C)O[C@H]([C@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)\C=C(/C)\C(\C)=C\C=C\C(\C)=C/C#N)OC)[C@H](OP(O)(O)=O)C3(C)C)co1)N(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
