Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50128358 (CHEMBL3629347) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of human recombinant melanocortin 4 receptor expressed in CHO cells | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50176065 (4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]4-DAMP from human recombinant Muscarinic acetylcholine receptor M3 expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]methyl-spiperone from human recombinant D2S receptor in HEK293 cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor in HEK293 cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]U 69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM22567 (3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor in HEK293 cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM28582 (1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [125I](+/-)DOI from human recombinant 5-HT2B receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (Homo sapiens (Human)) | BDBM50233962 (CHEMBL4068783) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [125I]NKA from human recombinant tachykinin NK2 receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50176062 (3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | DrugBank Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human recombinant norepinephrine transporter expressed in CHO cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50005534 (1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]BTCP from human recombinant dopamine transporter expressed in CHO cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM39341 (11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]pirenzepine from human recombinant Muscarinic acetylcholine receptor M1 expressed in CHO cells after 60 mins by scintillation cou... | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5-HT6 receptor expressed in CHO cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5-HT5a receptor in HEK293 cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Homo sapiens (Human)) | BDBM181119 (US9138393, Cimetidine | US9144538, Cimetidine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50061067 (15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275R | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50061067 (15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild type | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50061067 (15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220V | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110686 (14-Ethylidene-2-isopropyl-5-(6-methoxy-3,5-dimethy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50061067 (15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50110681 (CHEMBL430266 | Calyculin-A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220V | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50128358 (CHEMBL3629347) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of human recombinant melanocortin 4 receptor expressed in CHO cells | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110681 (CHEMBL430266 | Calyculin-A) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110685 (25-Isobutyl-15-(6-methoxy-3,5-dimethyl-7-phenyl-he...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50176065 (4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]4-DAMP from human recombinant Muscarinic acetylcholine receptor M3 expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50110681 (CHEMBL430266 | Calyculin-A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275R | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50110681 (CHEMBL430266 | Calyculin-A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild type | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50110681 (CHEMBL430266 | Calyculin-A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibitory concentration against Protein phosphatase 1 was determined; 0.5-1.0 | Bioorg Med Chem Lett 12: 391-3 (2002) BindingDB Entry DOI: 10.7270/Q2XS5VX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor in HEK293 cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50061067 (15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127S | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]U 69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50366883 (TAUTOMYCIN) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50061067 (15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in Y272F | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.810 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]methyl-spiperone from human recombinant D2S receptor in HEK293 cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110676 (CHEMBL280487 | okadaic acid) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110676 (CHEMBL280487 | okadaic acid) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Concentration required to inhibit the action of protein phosphatase 2A | Bioorg Med Chem Lett 12: 391-3 (2002) BindingDB Entry DOI: 10.7270/Q2XS5VX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110682 (25-Isobutyl-15-(6-methoxy-3,5-dimethyl-7-phenyl-he...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110700 (7-Cyclohexyl-25-isobutyl-15-(6-methoxy-3,5-dimethy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM22567 (3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor in HEK293 cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50061067 (15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D208A | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110681 (CHEMBL430266 | Calyculin-A) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Concentration required to inhibit the action of protein phosphatase 2A | Bioorg Med Chem Lett 12: 391-3 (2002) BindingDB Entry DOI: 10.7270/Q2XS5VX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (Homo sapiens (Human)) | BDBM50110681 (CHEMBL430266 | Calyculin-A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127S | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50176062 (3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | DrugBank Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human recombinant norepinephrine transporter expressed in CHO cells after 120 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM28582 (1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [125I](+/-)DOI from human recombinant 5-HT2B receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110690 (CHEMBL17377 | FOSTRIECIN | Phosphoric acid mono-{3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110693 (25-Cyclohexylmethyl-15-(6-methoxy-3,5-dimethyl-7-p...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110690 (CHEMBL17377 | FOSTRIECIN | Phosphoric acid mono-{3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibitory activity against partially purified (chicken skeletal muscle) Protein phosphatase 2A | Bioorg Med Chem Lett 10: 1687-90 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6Z8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-K receptor (Homo sapiens (Human)) | BDBM50233962 (CHEMBL4068783) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Displacement of [125I]NKA from human recombinant tachykinin NK2 receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 60: 349-361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01422 BindingDB Entry DOI: 10.7270/Q27M0B6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B (Gallus gallus) | BDBM50110694 (11,22-Dicarboxy-25-isobutyl-15-(6-methoxy-3,5-dime...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac) | J Med Chem 45: 1151-75 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5GCG | |||||||||||
More data for this Ligand-Target Pair |
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