Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Melanocortin receptor 4 | ||
| Ligand | BDBM50119368 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_106190 | ||
| EC50 | 4±n/a nM | ||
| Citation |  Dyck, B; Parker, J; Phillips, T; Carter, L; Murphy, B; Summers, R; Hermann, J; Baker, T; Cismowski, M; Saunders, J; Goodfellow, V Aryl piperazine melanocortin MC4 receptor agonists. Bioorg Med Chem Lett13:3793-6 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Melanocortin receptor 4 | |||
| Name: | Melanocortin receptor 4 | ||
| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36949.50 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P32245 | ||
| Residue: | 332 | ||
| Sequence: |
| ||
| BDBM50119368 | |||
| n/a | |||
| Name | BDBM50119368 | ||
| Synonyms: | (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide | (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-cyclohexyl-4-(3H-[1,2,4]triazol-1-ylmethyl)-piperidin-1-yl]-2-oxo-ethyl}-amide | (R)-N-((R)-1-(4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide | 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide | 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide | CHEMBL339053 | THIQ | ||
| Type | Small organic molecule | ||
| Emp. Form. | C33H41ClN6O2 | ||
| Mol. Mass. | 589.171 | ||
| SMILES | Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1 | ||
| Structure | 
| ||