Reaction Details |
| Report a problem with these data |
Target | Adenylate kinase 2, mitochondrial |
---|
Ligand | BDBM18137 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_32057 (CHEMBL644155) |
---|
Ki | 80000±n/a nM |
---|
Citation | Kappler, F; Hai, TT; Abo, M; Hampton, A Species- or isozyme-specific enzyme inhibitors. 8. Synthesis of disubstituted two-substrate condensation products as inhibitors of rat adenylate kinases. J Med Chem25:1179-84 (1983) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Adenylate kinase 2, mitochondrial |
---|
Name: | Adenylate kinase 2, mitochondrial |
Synonyms: | 2.7.4.3 | AK 2 | ATP-AMP transphosphorylase 2 | ATP:AMP phosphotransferase | Adenylate kinase 2 | Adenylate kinase 2, mitochondrial | Adenylate monophosphate kinase | Ak2 | KAD2_RAT |
Type: | n/a |
Mol. Mass.: | 26380.21 |
Organism: | Rattus norvegicus |
Description: | n/a |
Residue: | 239 |
Sequence: | MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSEL
GKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKE
KLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNE
KALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV
|
|
|
BDBM18137 |
---|
n/a |
---|
Name | BDBM18137 |
Synonyms: | AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,4R,5R)-5-adenin-9-yl-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate;hydrate | adenosine 5 -monophosphate | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid |
Type | Nucleoside or nucleotide |
Emp. Form. | C10H14N5O7P |
Mol. Mass. | 347.2212 |
SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O |
Structure |
|