Reaction Details |
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Target | Adenylate kinase 2, mitochondrial |
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Ligand | BDBM50366480 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_32055 (CHEMBL874426) |
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Ki | 90000±n/a nM |
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Citation | Kappler, F; Hai, TT; Abo, M; Hampton, A Species- or isozyme-specific enzyme inhibitors. 8. Synthesis of disubstituted two-substrate condensation products as inhibitors of rat adenylate kinases. J Med Chem25:1179-84 (1983) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Adenylate kinase 2, mitochondrial |
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Name: | Adenylate kinase 2, mitochondrial |
Synonyms: | 2.7.4.3 | AK 2 | ATP-AMP transphosphorylase 2 | ATP:AMP phosphotransferase | Adenylate kinase 2 | Adenylate kinase 2, mitochondrial | Adenylate monophosphate kinase | Ak2 | KAD2_RAT |
Type: | n/a |
Mol. Mass.: | 26380.21 |
Organism: | Rattus norvegicus |
Description: | n/a |
Residue: | 239 |
Sequence: | MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSEL
GKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKE
KLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNE
KALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV
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BDBM50366480 |
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n/a |
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Name | BDBM50366480 |
Synonyms: | ADENOSINE TRIPHOSPHATE | ATP |
Type | Small organic molecule |
Emp. Form. | C10H16N5O13P3 |
Mol. Mass. | 507.181 |
SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
Structure |
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