| Reaction Details |
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 | Report a problem with these data |
| Target | Pyruvate kinase PKLR |
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| Ligand | BDBM50367050 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_160243 (CHEMBL767857) |
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| Ki | 10900000±n/a nM |
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| Citation |  Hai, TT; Abo, M; Hampton, A Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem25:1184-8 (1983) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pyruvate kinase PKLR |
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| Name: | Pyruvate kinase PKLR |
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| Synonyms: | KPYR_RAT | Pklr | Pyruvate kinase isozymes R/L |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62202.26 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1359662 |
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| Residue: | 574 |
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| Sequence: | MSVQENTLPQQLWPWIFRSQKDLAKSALSGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ
LPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFS
HGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKG
SQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEV
EHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDA
LGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC
NLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMM
QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRS
AQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESG
KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVS
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| BDBM50367050 |
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| n/a |
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| Name | BDBM50367050 |
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| Synonyms: | CHEMBL606006 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17N5O10P2 |
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| Mol. Mass. | 441.2277 |
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| SMILES | C[C@@H](OP(O)(=O)OP(O)(O)=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| |
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| Structure | 
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