| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pyruvate kinase PKLR |
|---|
| Ligand | BDBM50367052 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_160244 (CHEMBL767858) |
|---|
| Ki | 1600000±n/a nM |
|---|
| Citation |  Hai, TT; Abo, M; Hampton, A Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem25:1184-8 (1983) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pyruvate kinase PKLR |
|---|
| Name: | Pyruvate kinase PKLR |
|---|
| Synonyms: | KPYR_RAT | Pklr | Pyruvate kinase isozymes R/L |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 62202.26 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1359662 |
|---|
| Residue: | 574 |
|---|
| Sequence: | MSVQENTLPQQLWPWIFRSQKDLAKSALSGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ
LPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFS
HGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKG
SQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEV
EHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDA
LGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC
NLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMM
QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRS
AQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESG
KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVS
|
|
|
|---|
| BDBM50367052 |
|---|
| n/a |
|---|
| Name | BDBM50367052 |
|---|
| Synonyms: | CHEMBL605425 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H22N6O10P2 |
|---|
| Mol. Mass. | 484.2955 |
|---|
| SMILES | CCCNc1nc2c(N)ncnc2n1C1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
