| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Renin |
|---|
| Ligand | BDBM50367762 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_196299 |
|---|
| IC50 | 105000±n/a nM |
|---|
| Citation |  Hui, KY; Holtzman, EJ; Quinones, MA; Hollenberg, NK; Haber, E Design of rat renin inhibitory peptides. J Med Chem31:1679-86 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Renin |
|---|
| Name: | Renin |
|---|
| Synonyms: | RENI_RAT | Ren | Ren1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44272.67 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_222765 |
|---|
| Residue: | 402 |
|---|
| Sequence: | MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGE
FIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYT
ACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG
GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSL
QLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL
ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
|
|
|
|---|
| BDBM50367762 |
|---|
| n/a |
|---|
| Name | BDBM50367762 |
|---|
| Synonyms: | CHEMBL1790272 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C47H69N13O11 |
|---|
| Mol. Mass. | 992.1313 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CCCN1)[C@@H](O)CC(=O)N[C@@H]([C@H](C)O)C(=O)N[C@@H]([C@H](C)O)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
