Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50016858 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_148701 |
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IC50 | 20000±n/a nM |
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Citation | Landis, G; Lui, G; Shook, JE; Yamamura, HI; Burks, TF; Hruby, VJ Synthesis of highly mu and delta opioid receptor selective peptides containing a photoaffinity group. J Med Chem32:638-43 (1989) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44503.11 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
Residue: | 398 |
Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50016858 |
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n/a |
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Name | BDBM50016858 |
Synonyms: | 2-{[16-(4-Amino-benzyl)-10-(4-amino-butyl)-19-(2-amino-3-phenyl-propionylamino)-7-(1-hydroxy-ethyl)-13-(1H-indol-3-ylmethyl)-3,3-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicosane-4-carbonyl]-amino}-3-hydroxy-butyramide | CHEMBL2371212 |
Type | Small organic molecule |
Emp. Form. | C51H68N14O10S2 |
Mol. Mass. | 1101.303 |
SMILES | [H][C@]1(NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(cc2)N=[N+]=[N-])NC(=O)[C@@H](CSSC(C)(C)[C@@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O |
Structure |
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