| Reaction Details |
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 | Report a problem with these data |
| Target | Transporter |
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| Ligand | BDBM50010874 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_177401 |
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| IC50 | 300±n/a nM |
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| Citation |  Yardley, JP; Husbands, GE; Stack, G; Butch, J; Bicksler, J; Moyer, JA; Muth, EA; Andree, T; Fletcher, H; James, MN 2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: synthesis and antidepressant activity. J Med Chem33:2899-905 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Transporter |
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| Name: | Transporter |
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| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66787.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1463061 |
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| Residue: | 597 |
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| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
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| BDBM50010874 |
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| n/a |
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| Name | BDBM50010874 |
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| Synonyms: | 1-(1-(4-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol | 1-[1-(4-Chloro-phenyl)-2-dimethylamino-ethyl]-cyclohexanol (HCl) | CHEMBL420644 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24ClNO |
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| Mol. Mass. | 281.821 |
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| SMILES | CN(C)CC(c1ccc(Cl)cc1)C1(O)CCCCC1 |
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| Structure | 
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