| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, NMDA 1 |
|---|
| Ligand | BDBM50002700 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_140542 |
|---|
| Ki | 1480±n/a nM |
|---|
| Citation |  McQuaid, LA; Smith, EC; South, KK; Mitch, CH; Schoepp, DD; True, RA; Calligaro, DO; O'Malley, PJ; Lodge, D; Ornstein, PL Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones. J Med Chem35:3319-24 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glutamate receptor ionotropic, NMDA 1 |
|---|
| Name: | Glutamate receptor ionotropic, NMDA 1 |
|---|
| Synonyms: | Glutamate (NMDA) receptor subunit zeta 1 | Glutamate [NMDA] receptor subunit zeta-1 | Glutamate-NMDA-Channel | Glutamate-NMDA-MK801 | Glutamate-NMDA-Polyamine | Grin1 | NMDA | NMDZ1_RAT | Nmdar1 | phencyclidine |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 105533.40 |
|---|
| Organism: | RAT |
|---|
| Description: | P35439 |
|---|
| Residue: | 938 |
|---|
| Sequence: | MSTMHLLTFALLFSCSFARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQL
NATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLG
LTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRL
ETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLNM
TGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKEN
ITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRK
LVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTC
KEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVA
DGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTI
LVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDA
LTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRP
EERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQA
VRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSH
ENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRH
KDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDT
STGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES
|
|
|
|---|
| BDBM50002700 |
|---|
| n/a |
|---|
| Name | BDBM50002700 |
|---|
| Synonyms: | 1-Butyl-7,8-dichloro-5H-[1,2,4]triazolo[4,3-a]quinoxalin-4-one | CHEMBL112193 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H12Cl2N4O |
|---|
| Mol. Mass. | 311.167 |
|---|
| SMILES | CCCCc1nnc2n1c1cc(Cl)c(Cl)cc1[nH]c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
