| Reaction Details |
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 | Report a problem with these data |
| Target | Neutral alpha-glucosidase AB |
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| Ligand | BDBM18351 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32946 (CHEMBL646336) |
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| Ki | 410000±n/a nM |
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| Citation |  Asano, N; Oseki, K; Kizu, H; Matsui, K Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases. J Med Chem37:3701-6 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutral alpha-glucosidase AB |
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| Name: | Neutral alpha-glucosidase AB |
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| Synonyms: | Alpha-glucosidase 2 | G2AN | GANAB | GANAB_HUMAN | Glucosidase II subunit alpha | KIAA0088 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 106864.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_218093 |
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| Residue: | 944 |
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| Sequence: | MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY
RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV
ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH
QRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYG
PMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVP
VLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETG
IIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHN
LPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVH
EELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVW
NDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVL
ARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELL
VRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHR
EGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQ
SYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTA
QGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKP
AAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR
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| BDBM18351 |
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| n/a |
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| Name | BDBM18351 |
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| Synonyms: | (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol, 10 | (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | 1-Deoxynojirimycin | 1-deoxynojirimycin (DNJ) | CHEMBL307429 | US20230339856, Compound DNJ | US9181184, 1 | dNM |
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| Type | natural product |
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| Emp. Form. | C6H13NO4 |
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| Mol. Mass. | 163.1717 |
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| SMILES | OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O |
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| Structure | 
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