| Reaction Details |
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 | Report a problem with these data |
| Target | Lysosomal alpha-glucosidase |
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| Ligand | BDBM50407255 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34416 (CHEMBL649420) |
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| IC50 | 55000±n/a nM |
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| Citation |  Asano, N; Oseki, K; Kizu, H; Matsui, K Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases. J Med Chem37:3701-6 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysosomal alpha-glucosidase |
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| Name: | Lysosomal alpha-glucosidase |
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| Synonyms: | Acidic alpha-glucosidase | Gaa | LYAG_RAT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 106191.24 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1506157 |
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| Residue: | 953 |
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| Sequence: | MNIRKPLCSNSVVGACTLVSLTTAVILGHLMLRELMLLPQDLHESSSGLWKTYRPHHQES
YEPAPLHIQEHAEQLRAVPTQCDVTPNSRFDCAPDKGITQEQCEARGCCWVPAGQVLNGP
VMGQPWCFFPPSYPSYRLENLSSTESGYTATLTRTSPTFFPKDVLTLQLEVLMETDSRLH
FMIKDPTSKRYEVPLETPRVLSQAPSPLYSVEFSEEPFGVIVRRKLGGRVLLNTTVAPLF
FADQFLQLSTSLPSQHIAGLGEHLSPLMLSTEWTRITLWNRDVAPSQGVNLYGSHPFYLA
LEDGGLAHGVFLLNSNAMDVVLQPSPALTWRSTGGILDVYVFLGPEPKSVVQQYLDVVGY
PFMPPYWGLGFHLCRWGYSSTAIVRQVVENMTRTHFPLDVQWNDLDYMDARRDFTFNQDG
FADFPDMVHELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKV
WPGSTAFPDFTNPETLDWWQDMVSEFHAQVPFDGMWIDMNEPSNFIRGSQQGCPDNELEN
PPYVPGVVGGALQAATICASSHQFLSTHYNLHNLYGLTEAIASSRALVKTRGTRPFVISR
STFAGHGRYAGHWTGDVWSSWEHLAYSVPEILQFNLLGVPLVGADICGFQGNTTEELCVR
WTQLGAFYPFMRNHNDLNSLPQEPYRFSETAQQAMRKAFTLRYALLPYLYTLFHGAHVKG
DTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTDVTGYFPKGMWYNLQMVPV
ETLGSLPSSSPASSFRSIVHSKGQWLTLEAPLDTINVHLRAGYIIPLQGPSLTTTESRKQ
PMALAVALTESGEASGELFWDDGESLGVLERGAYTLVTFSAKNNTIVNKLVHVTKEGGEL
QLREVTILGVTTAPTQVLSNGISVSNFTYSPDDKSLSIPVSLLMGERFQIDWS
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| BDBM50407255 |
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| n/a |
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| Name | BDBM50407255 |
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| Synonyms: | CHEMBL2114189 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H13NO2 |
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| Mol. Mass. | 131.1729 |
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| SMILES | CC[C@H]1NC[C@@H](O)[C@@H]1O |r| |
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| Structure | 
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