| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50038755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_155148 (CHEMBL760189) |
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| IC50 | 73±n/a nM |
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| Citation |  Fray, MJ; Bull, DJ; Cooper, K; Parry, MJ; Stefaniak, MH Novel antagonists of platelet-activating factor. 2. Synthesis and structure-activity relationships of potent and long-acting heterofused [1,5]benzodiazepine and [1,4]diazepine derivatives of 2-methyl-1-phenylimidazo[4,5-c]pyridine. J Med Chem38:3524-35 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50038755 |
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| n/a |
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| Name | BDBM50038755 |
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| Synonyms: | 6-(2-chlorophenyl)-1-methyl-8,9-dihydro-4H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-9-yl-1,4-oxazinan-4-ylmethanone (WEB 2170) | Bepafant |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22ClN5O2S |
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| Mol. Mass. | 467.971 |
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| SMILES | Cc1nnc2CN=C(c3c4CC(Cc4sc3-n12)C(=O)N1CCOCC1)c1ccccc1Cl |c:6| |
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| Structure | 
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