| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
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| Ligand | BDBM50061276 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48586 (CHEMBL662466) |
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| IC50 | 217±n/a nM |
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| Citation |  Bellier, B; McCort-Tranchepain, I; Ducos, B; Danascimento, S; Meudal, H; Noble, F; Garbay, C; Roques, BP Synthesis and biological properties of new constrained CCK-B antagonists: discrimination of two affinity states of the CCK-B receptor on transfected CHO cells. J Med Chem40:3947-56 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin/cholecystokinin type B receptor |
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| Name: | Gastrin/cholecystokinin type B receptor |
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| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin B receptor | Cholecystokinin receptor | GASR_RAT | Gastrin/cholecystokinin type B receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48980.43 |
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| Organism: | RAT |
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| Description: | Cholecystokinin A CCKBR RAT::P30553 |
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| Residue: | 452 |
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| Sequence: | MELLKLNRSVQGPGPGSGSSLCRPGVSLLNSSSAGNLSCDPPRIRGTGTRELEMAIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAISYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTMVQPVGPRVLQCMHRWPSARVQQTWSVLLLLLLFFIPGVVIAVAYGL
ISRELYLGLHFDGENDSETQSRARNQGGLPGGAAPGPVHQNGGCRPVTSVAGEDSDGCCV
QLPRSRLEMTTLTTPTPGPVPGPRPNQAKLLAKKRVVRMLLVIVLLFFLCWLPVYSVNTW
RAFDGPGAQRALSGAPISFIHLLSYVSACVNPLVYCFMHRRFRQACLDTCARCCPRPPRA
RPQPLPDEDPPTPSIASLSRLSYTTISTLGPG
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| BDBM50061276 |
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| n/a |
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| Name | BDBM50061276 |
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| Synonyms: | (R)-1-[(R)-2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionyl]-4-(4-chloro-phenyl)-pyrrolidine-2-carboxylic acid | CHEMBL338526 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H38ClN3O5 |
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| Mol. Mass. | 604.136 |
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| SMILES | n/a |
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| Structure | 
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