| Reaction Details |
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 | Report a problem with these data |
| Target | Steryl-sulfatase |
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| Ligand | BDBM50369434 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_67986 (CHEMBL679542) |
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| IC50 | 80±n/a nM |
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| Citation |  Hejaz, HA; Purohit, A; Mahon, MF; Reed, MJ; Potter, BV Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene. J Med Chem42:3188-92 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Steryl-sulfatase |
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| Name: | Steryl-sulfatase |
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| Synonyms: | ARSC1 | ASC | Arylsulfatase C | STS | STS_HUMAN | Steroid sulfatase | Steryl-sulfate sulfohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 65503.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08842 |
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| Residue: | 583 |
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| Sequence: | MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLAS
GGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAK
LLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTT
GFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPL
NCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFA
GKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGS
NGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRI
IDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNG
CFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQT
LPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR
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| BDBM50369434 |
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| n/a |
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| Name | BDBM50369434 |
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| Synonyms: | CHEMBL1627551 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24N2O4S |
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| Mol. Mass. | 364.459 |
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| SMILES | C[C@]12CC[C@H]3[C@@H](CCc4cc(OS(N)(=O)=O)ccc34)[C@@H]1CCC2N=O |
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| Structure | 
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