| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50084243 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146669 (CHEMBL755872) |
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| Ki | 10000±n/a nM |
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| Citation |  Zhang, X; Rice, KC; Calderon, SN; Kayakiri, H; Smith, L; Coop, A; Jacobson, AE; Rothman, RB; Davis, P; Dersch, CM; Porreca, F Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands. J Med Chem42:5455-63 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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|
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| BDBM50084243 |
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| n/a |
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| Name | BDBM50084243 |
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| Synonyms: | 4-[(2-Dimethylamino-ethoxy)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide; oxalic acid | CHEMBL150785 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H32N2O3 |
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| Mol. Mass. | 384.5118 |
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| SMILES | CCN(CC)C(=O)c1ccc(cc1)C(OCCN(C)C)c1cccc(OC)c1 |
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| Structure | 
|
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