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TargetCholecystokinin receptor type A
LigandBDBM50092157
Substrate/Competitorn/a
Meas. Tech.ChEMBL_50175 (CHEMBL662233)
IC50 6400±n/a nM
Citation Low, CM; Black, JW; Broughton, HB; Buck, IM; Davies, JM; Dunstone, DJ; Hull, RA; Kalindjian, SB; McDonald, IM; Pether, MJ; Shankley, NP; Steel, KI Development of peptide 3D structure mimetics: rational design of novel peptoid cholecystokinin receptor antagonists. J Med Chem43:3505-17 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Cholecystokinin receptor type A
Name:Cholecystokinin receptor type A
Synonyms:CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:Enzyme Catalytic Domain
Mol. Mass.:49676.37
Organism:RAT
Description:Cholecystokinin central 0 RAT::P30551
Residue:444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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BDBM50092157
n/a
NameBDBM50092157
Synonyms:(4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carboxylic acid (4-bromo-phenyl)-amide | (4R,5S)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazolidine-1-carboxamide | 3-Oxo-4,5-diphenyl-pyrazolidine-1-carboxylic acid (4-bromo-phenyl)-amide(LY288512) | CHEMBL117281 | LY-288512
TypeSmall organic molecule
Emp. Form.C22H18BrN3O2
Mol. Mass.436.301
SMILESBrc1ccc(NC(=O)N2NC(=O)[C@@H]([C@H]2c2ccccc2)c2ccccc2)cc1
Structure
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