| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50083922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29137 (CHEMBL637559) |
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| Ki | 141.2±n/a nM |
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| Citation |  Da Settimo, F; Primofiore, G; Taliani, S; Marini, AM; La Motta, C; Novellino, E; Greco, G; Lavecchia, A; Trincavelli, L; Martini, C 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists. J Med Chem44:316-27 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50083922 |
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| n/a |
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| Name | BDBM50083922 |
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| Synonyms: | 3-Phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one | CHEMBL7113 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10N4O |
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| Mol. Mass. | 262.2661 |
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| SMILES | O=c1c(nnc2[nH]c3ccccc3n12)-c1ccccc1 |
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| Structure | 
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