| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50102286 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30744 (CHEMBL649775) |
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| Ki | 1236±n/a nM |
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| Citation |  Da Settimo, F; Primofiore, G; Taliani, S; Marini, AM; La Motta, C; Novellino, E; Greco, G; Lavecchia, A; Trincavelli, L; Martini, C 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists. J Med Chem44:316-27 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50102286 |
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| n/a |
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| Name | BDBM50102286 |
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| Synonyms: | 10-benzyl-3-furan-2-yl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one | CHEMBL113518 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14N4O2 |
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| Mol. Mass. | 342.3508 |
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| SMILES | O=c1c(nnc2n(Cc3ccccc3)c3ccccc3n12)-c1ccco1 |
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| Structure | 
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