| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50118162 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86900 (CHEMBL698410) |
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| Ki | 44±n/a nM |
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| Citation |  Sasse, A; Ligneau, X; Rouleau, A; Elz, S; Ganellin, CR; Arrang, JM; Schwartz, JC; Schunack, W; Stark, H Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties. J Med Chem45:4000-10 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50118162 |
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| n/a |
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| Name | BDBM50118162 |
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| Synonyms: | (Cyclopropyl-phenyl-methyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester;0.8C2H2O4 | CHEMBL128585 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21N3O2 |
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| Mol. Mass. | 299.3675 |
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| SMILES | O=C(NC(C1CC1)c1ccccc1)OCCCc1cnc[nH]1 |
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| Structure | 
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