Compile Data Set for Download or QSAR

Found 131 hits with Last Name = 'sasse' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091385 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H17N3O2/c1-11(17-18)12-4-6-14(7-5-12)19-8-2-3-13-9-15-10-16-13/h4-7,9-11H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091373 (1-{2-Fluoro-4-[3-(1H-imidazol-4-yl)-propoxy]-pheny...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1F Show InChI InChI=1S/C14H16FN3O2/c1-10(18-19)13-5-4-12(7-14(13)15)20-6-2-3-11-8-16-9-17-11/h4-5,7-10H,2-3,6H2,1H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091396 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzaldehyde oxim...) Show SMILES O=NCc1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H15N3O2/c17-16-8-11-3-5-13(6-4-11)18-7-1-2-12-9-14-10-15-12/h3-6,9-10H,1-2,7-8H2,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091382 (CHEMBL324724 | N-Hydroxy-4-[3-(1H-imidazol-4-yl)-p...) Show SMILES ONC(=N)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H16N4O2/c14-13(17-18)10-3-5-12(6-4-10)19-7-1-2-11-8-15-9-16-11/h3-6,8-9,18H,1-2,7H2,(H2,14,17)(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM27213 (4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...) Show SMILES O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22541 (Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...) Show SMILES NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| Show InChI InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091386 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES CC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H16N2O2/c1-11(17)12-4-6-14(7-5-12)18-8-2-3-13-9-15-10-16-13/h4-7,9-10H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091372 (CHEMBL322481 | N-(1-{4-[3-(1H-Imidazol-4-yl)-propo...) Show SMILES CC(NO)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H19N3O2/c1-11(17-18)12-4-6-14(7-5-12)19-8-2-3-13-9-15-10-16-13/h4-7,9-11,17-18H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091371 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2-methyl-pheny...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1C Show InChI InChI=1S/C15H19N3O2/c1-11-8-14(5-6-15(11)12(2)18-19)20-7-3-4-13-9-16-10-17-13/h5-6,8-10,12H,3-4,7H2,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091384 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzoic acid hydr...) Show SMILES NNC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H16N4O2/c14-17-13(18)10-3-5-12(6-4-10)19-7-1-2-11-8-15-9-16-11/h3-6,8-9H,1-2,7,14H2,(H,15,16)(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091375 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-3-methyl-pheny...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)c(C)c1 Show InChI InChI=1S/C15H19N3O2/c1-11-8-13(12(2)18-19)5-6-15(11)20-7-3-4-14-9-16-10-17-14/h5-6,8-10,12H,3-4,7H2,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091383 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-propan...) Show SMILES CCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H19N3O2/c1-2-15(18-19)12-5-7-14(8-6-12)20-9-3-4-13-10-16-11-17-13/h5-8,10-11,15H,2-4,9H2,1H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091389 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzoic acid meth...) Show SMILES COC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H16N2O3/c1-18-14(17)11-4-6-13(7-5-11)19-8-2-3-12-9-15-10-16-12/h4-7,9-10H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074066 (CHEMBL154478 | Heptyl-carbamic acid 3-(1H-imidazol...) Show SMILES CCCCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C14H25N3O2/c1-2-3-4-5-6-9-16-14(18)19-10-7-8-13-11-15-12-17-13/h11-12H,2-10H2,1H3,(H,15,17)(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091376 (CHEMBL116270 | CHEMBL80348 | Cyclopropyl-{4-[3-(1H...) Show SMILES O=NC(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H19N3O2/c20-19-16(12-3-4-12)13-5-7-15(8-6-13)21-9-1-2-14-10-17-11-18-14/h5-8,10-12,16H,1-4,9H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091398 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-butan-...) Show SMILES CCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H21N3O2/c1-2-4-16(19-20)13-6-8-15(9-7-13)21-10-3-5-14-11-17-12-18-14/h6-9,11-12,16H,2-5,10H2,1H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091397 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-pentan...) Show SMILES CCCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C17H23N3O2/c1-2-3-6-17(20-21)14-7-9-16(10-8-14)22-11-4-5-15-12-18-13-19-15/h7-10,12-13,17H,2-6,11H2,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074076 ((3-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-y...) Show SMILES CCC(C)CCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-11(2)6-7-15-13(17)18-8-4-5-12-9-14-10-16-12/h9-11H,3-8H2,1-2H3,(H,14,16)(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074061 (CHEMBL346573 | Octyl-carbamic acid 3-(1H-imidazol-...) Show SMILES CCCCCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C15H27N3O2/c1-2-3-4-5-6-7-10-17-15(19)20-11-8-9-14-12-16-13-18-14/h12-13H,2-11H2,1H3,(H,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50118157 (CHEMBL128635 | [1-(1-Methyl-cyclopropyl)-ethyl]-ca...) Show SMILES CC(NC(=O)OCCCc1cnc[nH]1)C1(C)CC1 Show InChI InChI=1S/C13H21N3O2/c1-10(13(2)5-6-13)16-12(17)18-7-3-4-11-8-14-9-15-11/h8-10H,3-7H2,1-2H3,(H,14,15)(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortex				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091388 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-butan-...) Show SMILES CCCC(O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H22N2O2/c1-2-4-16(19)13-6-8-15(9-7-13)20-10-3-5-14-11-17-12-18-14/h6-9,11-12,16,19H,2-5,10H2,1H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091387 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzamide; compou...) Show SMILES NC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H15N3O2/c14-13(17)10-3-5-12(6-4-10)18-7-1-2-11-8-15-9-16-11/h3-6,8-9H,1-2,7H2,(H2,14,17)(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50118151 (4-[3-(4,4-Dimethyl-pentyloxy)-propyl]-1H-imidazole...) Show SMILES CC(C)(C)CCCOCCCc1cnc[nH]1 Show InChI InChI=1S/C13H24N2O/c1-13(2,3)7-5-9-16-8-4-6-12-10-14-11-15-12/h10-11H,4-9H2,1-3H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cells				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091390 (4-[3-(4-Nitro-phenoxy)-propyl]-1H-imidazole with(0...) Show SMILES [O-][N+](=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H13N3O3/c16-15(17)11-3-5-12(6-4-11)18-7-1-2-10-8-13-9-14-10/h3-6,8-9H,1-2,7H2,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091378 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES CC(O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H18N2O2/c1-11(17)12-4-6-14(7-5-12)18-8-2-3-13-9-15-10-16-13/h4-7,9-11,17H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50118157 (CHEMBL128635 | [1-(1-Methyl-cyclopropyl)-ethyl]-ca...) Show SMILES CC(NC(=O)OCCCc1cnc[nH]1)C1(C)CC1 Show InChI InChI=1S/C13H21N3O2/c1-10(13(2)5-6-13)16-12(17)18-7-3-4-11-8-14-9-15-11/h8-10H,3-7H2,1-2H3,(H,14,15)(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cells				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074082 ((3-Methyl-butyl)-carbamic acid 3-(1H-imidazol-4-yl...) Show SMILES CC(C)CCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-10(2)5-6-14-12(16)17-7-3-4-11-8-13-9-15-11/h8-10H,3-7H2,1-2H3,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370140 (CHEMBL1788227) Show SMILES C[C@@H](NC(=O)OCCCc1cnc[nH]1)C(C)(C)C |r| Show InChI InChI=1S/C13H23N3O2/c1-10(13(2,3)4)16-12(17)18-7-5-6-11-8-14-9-15-11/h8-10H,5-7H2,1-4H3,(H,14,15)(H,16,17)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cells				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50118159 (CHEMBL340932 | Dicyclopropylmethyl-carbamic acid 3...) Show SMILES O=C(NC(C1CC1)C1CC1)OCCCc1cnc[nH]1 Show InChI InChI=1S/C14H21N3O2/c18-14(17-13(10-3-4-10)11-5-6-11)19-7-1-2-12-8-15-9-16-12/h8-11,13H,1-7H2,(H,15,16)(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cells				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091393 ((4-(3-(1H-imidazol-4-yl)propyloxy)phenyl)ethanone ...) Show SMILES CC(=NNC(N)=O)c1ccc(OCCCc2cnc[nH]2)cc1 |w:2.2| Show InChI InChI=1S/C15H19N5O2/c1-11(19-20-15(16)21)12-4-6-14(7-5-12)22-8-2-3-13-9-17-10-18-13/h4-7,9-10H,2-3,8H2,1H3,(H,17,18)(H3,16,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074085 (CHEMBL154977 | Pentyl-carbamic acid 3-(1H-imidazol...) Show SMILES CCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-7-14-12(16)17-8-5-6-11-9-13-10-15-11/h9-10H,2-8H2,1H3,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074070 (CHEMBL156413 | Hexyl-carbamic acid 3-(1H-imidazol-...) Show SMILES CCCCCCNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-2-3-4-5-8-15-13(17)18-9-6-7-12-10-14-11-16-12/h10-11H,2-9H2,1H3,(H,14,16)(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074072 ((1-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-y...) Show SMILES CCCCC(C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-4-6-11(2)16-13(17)18-8-5-7-12-9-14-10-15-12/h9-11H,3-8H2,1-2H3,(H,14,15)(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50408755 (CHEMBL2145442) Show SMILES CC(C)CCCOCCCc1cnc[nH]1 Show InChI InChI=1S/C12H22N2O/c1-11(2)5-3-7-15-8-4-6-12-9-13-10-14-12/h9-11H,3-8H2,1-2H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370139 (CHEMBL1788247) Show SMILES C[C@@H](NC(=O)OCCCc1cnc[nH]1)C1CCCCC1 |r| Show InChI InChI=1S/C15H25N3O2/c1-12(13-6-3-2-4-7-13)18-15(19)20-9-5-8-14-10-16-11-17-14/h10-13H,2-9H2,1H3,(H,16,17)(H,18,19)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cells				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50409581 (CHEMBL2092970) Show SMILES C[C@H](NC(=O)OCCCc1cnc[nH]1)C(C)(C)C |r| Show InChI InChI=1S/C13H23N3O2/c1-10(13(2,3)4)16-12(17)18-7-5-6-11-8-14-9-15-11/h8-10H,5-7H2,1-4H3,(H,14,15)(H,16,17)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortex				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50118156 (4-[3-(3,3-Dimethyl-butoxy)-propyl]-1H-imidazole | ...) Show SMILES CC(C)(C)CCOCCCc1cnc[nH]1 Show InChI InChI=1S/C12H22N2O/c1-12(2,3)6-8-15-7-4-5-11-9-13-10-14-11/h9-10H,4-8H2,1-3H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortex				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50118156 (4-[3-(3,3-Dimethyl-butoxy)-propyl]-1H-imidazole | ...) Show SMILES CC(C)(C)CCOCCCc1cnc[nH]1 Show InChI InChI=1S/C12H22N2O/c1-12(2,3)6-8-15-7-4-5-11-9-13-10-14-11/h9-10H,4-8H2,1-3H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex				J Med Chem 42: 4269-74 (1999) BindingDB Entry DOI: 10.7270/Q2B85799
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50118159 (CHEMBL340932 | Dicyclopropylmethyl-carbamic acid 3...) Show SMILES O=C(NC(C1CC1)C1CC1)OCCCc1cnc[nH]1 Show InChI InChI=1S/C14H21N3O2/c18-14(17-13(10-3-4-10)11-5-6-11)19-7-1-2-12-8-15-9-16-12/h8-11,13H,1-7H2,(H,15,16)(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortex				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50118156 (4-[3-(3,3-Dimethyl-butoxy)-propyl]-1H-imidazole | ...) Show SMILES CC(C)(C)CCOCCCc1cnc[nH]1 Show InChI InChI=1S/C12H22N2O/c1-12(2,3)6-8-15-7-4-5-11-9-13-10-14-11/h9-10H,4-8H2,1-3H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cells				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074083 (((R)-1-Methyl-butyl)-carbamic acid 3-(1H-imidazol-...) Show SMILES CCC[C@@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-3-5-10(2)15-12(16)17-7-4-6-11-8-13-9-14-11/h8-10H,3-7H2,1-2H3,(H,13,14)(H,15,16)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074063 (((S)-1-Methyl-pentyl)-carbamic acid 3-(1H-imidazol...) Show SMILES CCCC[C@H](C)NC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H23N3O2/c1-3-4-6-11(2)16-13(17)18-8-5-7-12-9-14-10-15-12/h9-11H,3-8H2,1-2H3,(H,14,15)(H,16,17)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091370 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-hexan-...) Show SMILES CCCCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C18H25N3O2/c1-2-3-4-7-18(21-22)15-8-10-17(11-9-15)23-12-5-6-16-13-19-14-20-16/h8-11,13-14,18H,2-7,12H2,1H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091392 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzaldehyde O-me...) Show SMILES CO\N=C\c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H17N3O2/c1-18-17-9-12-4-6-14(7-5-12)19-8-2-3-13-10-15-11-16-13/h4-7,9-11H,2-3,8H2,1H3,(H,15,16)/b17-9+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50370140 (CHEMBL1788227) Show SMILES C[C@@H](NC(=O)OCCCc1cnc[nH]1)C(C)(C)C |r| Show InChI InChI=1S/C13H23N3O2/c1-10(13(2,3)4)16-12(17)18-7-5-6-11-8-14-9-15-11/h8-10H,5-7H2,1-4H3,(H,14,15)(H,16,17)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortex				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50118155 ((1,2,2-Trimethyl-propyl)-carbamic acid 3-(1H-imida...) Show SMILES CC(NC(=O)OCCCc1cnc[nH]1)C(C)(C)C Show InChI InChI=1S/C13H23N3O2/c1-10(13(2,3)4)16-12(17)18-7-5-6-11-8-14-9-15-11/h8-10H,5-7H2,1-4H3,(H,14,15)(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortex				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50118152 (4-[3-(5,5-Dimethyl-hexyloxy)-propyl]-1H-imidazole;...) Show SMILES CC(C)(C)CCCCOCCCc1cnc[nH]1 Show InChI InChI=1S/C14H26N2O/c1-14(2,3)8-4-5-9-17-10-6-7-13-11-15-12-16-13/h11-12H,4-10H2,1-3H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cells				J Med Chem 45: 4000-10 (2002) BindingDB Entry DOI: 10.7270/Q24F1RG3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50074064 ((2-Methyl-butyl)-carbamic acid 3-(1H-imidazol-4-yl...) Show SMILES CCC(C)CNC(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H21N3O2/c1-3-10(2)7-14-12(16)17-6-4-5-11-8-13-9-15-11/h8-10H,3-7H2,1-2H3,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Effect at histamine H3 receptors (in vitro) on synaptosomes of rat cerebral cortex assayed by functional H3-receptor assay.				J Med Chem 42: 593-600 (1999) Article DOI: 10.1021/jm9804376 BindingDB Entry DOI: 10.7270/Q2GH9H4J
					More data for this Ligand-Target Pair

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