| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM50409580 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_83478 (CHEMBL693949) |
|---|
| Kd | 19.95±n/a nM |
|---|
| Citation |  Sasse, A; Ligneau, X; Rouleau, A; Elz, S; Ganellin, CR; Arrang, JM; Schwartz, JC; Schunack, W; Stark, H Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties. J Med Chem45:4000-10 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48753.61 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
|
|
|
|---|
| BDBM50409580 |
|---|
| n/a |
|---|
| Name | BDBM50409580 |
|---|
| Synonyms: | CHEMBL131366 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H21N3O2 |
|---|
| Mol. Mass. | 239.314 |
|---|
| SMILES | CC(C)C(C)NC(=O)OCCCc1cnc[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
