| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Ligand | BDBM50110676 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197842 (CHEMBL806669) |
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| IC50 | 48±n/a nM |
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| Citation |  McCluskey, A; Sim, AT; Sakoff, JA Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies. J Med Chem45:1151-75 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Name: | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Synonyms: | PP1G_HUMAN | PPP1CC | Serine/threonine protein phosphatase PP1-gamma catalytic subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36983.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_473188 |
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| Residue: | 323 |
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| Sequence: | MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
KKKPNATRPVTPPRGMITKQAKK
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| BDBM50110676 |
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| n/a |
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| Name | BDBM50110676 |
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| Synonyms: | CHEMBL280487 | okadaic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C44H68O13 |
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| Mol. Mass. | 805.0029 |
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| SMILES | C[C@@H](C[C@H](O)[C@H]1O[C@@H]2CC[C@@]3(CC[C@@H](O3)\C=C\[C@@H](C)[C@@H]3CC(C)=C[C@@]4(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]4O)O3)O[C@H]2[C@H](O)C1=C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C |r,c:23| |
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| Structure | 
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